Aldactone (spironolactone): Another Success in Hormonal Acne Treatment

General overview

Aldactone is an oral medication used for a number of medical conditions. For more than two decades as a part of the dermatological setting. Though it’s excellent at treating acne, it’s only prescribed to women and has contraindications that need to be considered. It must only be taken by your specialist’s prescription. The generic name of the drug is spironolactone but it is sold under the brand name Aldactone.

Aldactone reduces acne by reducing the amount of androgen hormones in women. Androgens are responsible for a number of characteristics commonly considered to be male, such as body hair and muscles. Androgens are also present in the female body, but usually at lower levels. When androgen is responsible for acne, it’s usually a result of excess sebum (oil) production. Aldactone reduces androgen levels which reduces oil which reduces acne.

How to use Aldactone

The most commonly used dosage of spironolactone is between 50 to 100 mg daily. Dermatologists usually recommend 25 mg of the drug to start and then increase the dose slowly depending on the effectiveness of each dose

Possible side effects of Aldactone

There are many side effects associated with Aldactone, which is why doctors don’t prescribe it often. Side effects range from minor to to severe.

Minor side effects include:

The list of severe side effects associated with Aldactone is long:

  • abdominalcramping or tenderness
  • heartburn, indigestion
  • bleeding gums
  • bloody or black, tarry stool, clay-colored stool
  • constipation
  • bloody, cloudy, or dark urine
  • decrease in urine output or decrease in urine-concentrating ability
  • breast pain, chest pain
  • clear or bloody discharge from the nipple
  • inverted nipple
  • coma
  • confusion
  • convulsions
  • cough or hoarseness, sore throat
  • diarrhea
  • difficulty swallowing
  • dizziness
  • drowsiness, weakness
  • fast or irregular heartbeat
  • chills
  • fever with or without chills
  • headache
  • hives, itching, or rash
  • dry mouth, increased thirst
  • loss of appetite
  • lower back or side pain
  • lump in the breast or under the arm
  • muscle pain or cramps
  • muscle spasms or twitching
  • nausea, vomiting
  • painful or difficult urination
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness or swelling of the breast
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the face, fingers, feet, ankles, or lower legs
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • troubled breathing
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual bleeding or bruising
  • yellow eyes or skin

If any of these side effects occur, seek emergency help. Tell your doctor if you’re taking any other medication or have any allergies. Aldactone isn’t a good choice for you if you have kidney issues or a history (or family history) of breast cancer, uterine cancer, or ovarian cancer.

Symptoms of Aldactone overdose

The most severe side effects are caused by overdosing on Aldactone. Symptoms of an overdose include:

What are the precautions to consider?

Before taking Aldactone, tell your doctor or pharmacist about your allergies. Aldactone may contain inactive ingredients that can bring about allergic reactions or other issues. Similarly, inform them of your family health history, especially if there’s history of high blood potassium (hyperkalemia), inability to urinate (anuria), kidney issues, liver issues, untreated electrolyte imbalance (e.g. low sodium) and decreased adrenal gland function (Addison’s disease).

Because Aldactone may cause dizziness and/or tiredness, don’t drive or do activities that require mental readiness until you’re certain that you are able to do so properly and safely.

To avoid side effects like rapid/irregular heartbeat and difficulty breathing, limit caffeinated and/or sugary beverages like energy drinks.

Those who are older than 60 may be more vulnerable to the side effects of this medication.

Avoid this medication while pregnant or breast feeding unless absolutely necessary. The effects of Aldactone on pregnant women, the fetus, and breast milk are unknown, so discuss use with your doctor before using this medication. Similarly, tell your doctor if you become pregnant while taking this medication.


Interactions with other drugs

Do not start, stop, or change the dosage of Aldactone or any drugs you’re using in conjunction with Aldactone. Discuss possible changes with your doctor first.

Some drugs that may interact with spironolactone include:

Aldactone may mildly interact with certain medical tests (cortisol levels), perhaps bringing about false test outcomes.

Missed dosage

Take Aldactone around the same time every day, to maintain a consistent schedule. Missing a single dose is ok. If you remember that you missed a dose shortly after you were supposed to take it, go ahead and take the medication. Don’t take the missed dose if it’s almost time for the next, as the doubled amount can be too much for your body to handle.

Storing Aldactone

Store it far from light and chill. Do not store Aldactone in your bathroom. Keep all drugs far from children and pets. Aldactone should be stored at room temperature, below 25 C (77 F). Do not flush this medicine down the toilet unless advised to do as such. Appropriately dispose this drug when it is expired or found useless.

Tips to follow when taking Aldactone