Avodart – Dutasteride

Avodart contains dutasteride, which is a 5α-reductase inhibitor. It prevents testosterone conversion to dihydrotestosterone (DHT). Read the medication guide along with the medicine before using it and discuss with your doctor in detail if you have any query.

Uses of Avodart

Dutasteride is used to treat the symptoms of BPH (benign prostatic hyperplasia) or simply enlarged prostate. Avodart is used along other medicines usually, including Flomax. It relieves the symptoms of BPH including:

Avodart may also help in reducing the need for surgery for BPH patients. Note that it’s not approved as a drug to prevent prostate cancer. In fact it may increase the risk of developing a very serious form of cancer of prostate and thus shouldn’t be used as a prophylaxis. Use the medicine only when advised by the doctor. Like every medicine, it has its pros and cons. Discuss with your doctor if Avodart is the best-suited medicine for your condition. Children and women of any age should not take Avodart.

Dutasteride Vs. Finasteride

Both the drugs are approved by FDA for the treatment of BPH (benign prostatic hyperplasia) and both belong to the same class of drugs. However, finasteride only inhibits only type II and type III isoforms of 5α-reductase, while dutasteride inhibits all three. Also, finasteride has a shorter half-life of 8 hours as compared to dutasteride which is 5 weeks.

Side effects of Avodart

Avodartis associated with various side effects including:

Even after stopping the medicine, the sexual problems caused by the medicine continue in some men. If you experience any of these symptoms, talk to your pharmacist and discuss with him if the benefits of this medicine outweigh the side effects in your specific case. Serious allergic reaction to Avodart is rare; however if you experience any of these symptoms, rush to the hospital immediately to prevent any life-threatening situation. Symptoms of serious allergic reaction (anaphylaxis) include:

Not all possible side effects are listed here. If you experience any undesired results or any unexpected symptoms, stop using the medicine and contact your doctor as soon as possible.

Safety & Precautions

Before taking Avodart, tell your detailed past and current medical history to your doctor. Tell him all the medicines you’re using and if you’re allergic to dutasteride or finasteride or if you have any other allergies too. If you’re using any herbal or non-prescription drugs, tell that to your doctor too. This medicine should not be used by women generally, and especially during pregnancy and breast-feeding. Avodart should not be given to children. You are not supposed to donate blood while you’re using this medicine or even after stopping its use for at least 6 months. It’s important not to donate blood containing this drug, especially if your blood is being given to a pregnant woman. In case of overdosing, contact poison control center or go to the emergency room of a hospital immediately. Don’t give your medicine to anyone else, even if they have similar symptoms. While using dutasteride, routine medical examination should be done for prostate while laboratory investigation for PSA (prostate specific antigen) should also be done to see the prognosis and development of any side effects. In case you miss a dose, take the medicine as soon as possible. However if you remember the missed dose near the timing of next dose, skip the missed one and continue with the routine one. Don’t take double dose just to catch up and cover the missed dose. Storage tips for the storage of Avodart include:

Expired, unused or broken medicine should be disposed off properly. Don’t flush it in the water; instead consult your local waste disposal team for more details.

How should I take Avodart?

Use Avodart as advised by your doctor. Avoid taking larger or smaller doses or for a longer than prescribed duration. Read the instruction manual that comes with the medicine carefully. Usual advice to use Avodart includes:


Drug interactions

Drugs and medicines can interact with other medicines or herbal products being used with them and result in undesired effects. Drug interactions may reduce the efficiency of either one or all of the drugs involved or may increase their side effects. Drugs that usually interact with Avodart that your doctor should be informed about before taking it include:

This is not the complete list of drugs that may interact with dutasteride. Tell your doctor regarding other medicines and vitamin or other supplements too if you’re using them. Discuss in detail with your doctor regarding all the medicines and products that you are already using or when you plan to start using them along Avodart to rule out any possible drug interactions. Don’t change the dosage of Avodart or any other product that you’re using with it without discussing it with your doctor.