Doryx (Doxycycline hyclate)

General Overview

Doxycycline hyclate, also known by its brand name Doryx, is used to treat a wide range of bacterial infections, including those that cause acne. Doryx is additionally used to prevent malaria. This pharmaceutical is known as a tetracycline antibiotic. It works by ceasing the development of bacteria.


This antibiotic treats only for bacterial infections. It won’t work for viral infections like influenza or common cold. Pointless use or misuse of any antibiotic can cause lowered effectiveness of Doryx. This medication might likewise be used to treat some skin conditions like rosacea.

How to use Doryx?

Doryx is best taken by mouth on an empty stomach, no less than 1 hour before a meal or 2 hours after, normally 1 or 2 times every day or as coordinated by your specialist. Take Doryx with a full glass of water (8 ounces/240 milliliters) unless directed other way. On the off chance that stomach upset happens, take it with some food or milk. On the other hand, doxycycline hyclate may not work as well if you take it with food or milk or anything high in calcium, so ask your specialist in the event that you might take it that way. Try not to lie down for 10 minutes subsequent to taking this medicine.

Take Doryx 2 to 3 hours before, or in the wake of taking any items containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate. A few samples incorporate didanosine solutions, antacids, quinapril, vitamins/minerals, and dairy products like milk, yogurt, and calcium-advanced juice. These may bind with doxycycline, keeping your body from completely absorbing the medication.

At the point when using to prevent malaria, Doryx is generally taken once every day. Take the first dose of this drug 1 to 2 days before travel or as coordinated by your specialist. Keep on taking this prescription every day while in the malaria prevalent zone. After returning home, you ought to continue taking this solution for 4 more weeks. In the event that you can’t complete this course of doxycycline, contact your specialist.

Try not to crush or bite Doryx. Swallow the capsules whole. On the off chance that you experience issues swallowing the capsule, the capsule may be opened and the substance sprinkled onto cool fruit juice and taken quickly. Try not to harm or damage the pellets when opening up the tablet. Try not to bite the sustenance/medicine blend because doing as such may cause the medication to be discharged too rapidly, expanding side effects. Drink a glass of cool water after every dose to guarantee complete swallowing of the drug. The dose depends on your medicinal condition and reaction to treatment. For small children, the dose might likewise be calculated on weight.

Antibiotics work best when the amount of concentration in your body is kept at a steady level. Along these lines, take this medication at equally separated intervals. Keep on taking Doryx until the full recommended amount is done, regardless of the fact that indications vanish following a couple of days. Stopping the prescription too soon might permit bacteria to keep on developing, which might bring about an arrival of the infection. Tell your specialist if your condition perseveres or worsens.

What are the possible side effects?

Stomach upset, diarrhea, nausea, or vomiting might happen. If any of these effects hold on or decline, tell your specialist or drug specialist immediately. Keep in mind that your specialist has endorsed this medicine because he or she has judged that the advantage outweighs the danger of side effects. Most patients using this drug don’t have severe side effects.

Tell your specialist immediately in the event that you have any serious side effects, such as sunburn, troublesome swallowing and change in the amount of urine passed. Tetracycline medications, for example, doxycycline, might infrequently cause a serious intracranial pressure increase(intracranial hypertension-IH). The danger of this side impact is more noteworthy for ladies of childbearing age who are overweight or who have had IH previously. In the event that IH increases, it more often leaves after doxycycline is stopped. There is a chance of perpetual vision loss or visual impairment. Get treatment immediately if you experience: relentless/extreme cerebral pain, vision changes, (for example, obscured/twofold vision, diminished vision, sudden blindness) and continuous nausea/vomiting.

Doryx might infrequently cause a serious intestinal condition (Clostridium difficile-related diarrhea) because of a kind of resistant bacteria. This condition might happen amid treatment or weeks to months after treatment has ceased. Try not to use anti-diarrhea or narcotic pain drugs in the event that you have any of the accompanying side effects because these items might exacerbate them. Tell your specialist immediately in the event that you experience: persevering diarrhea, abdominal or stomach torment/cramping, blood in your stool.

Use of this solution for prolonged or repeated periods might bring about oral thrush or vaginal yeast infection. Contact your specialist if you see white patches in your mouth, a change in vaginal discharge, or other unusual symptoms. An intense allergic response to this medication is uncommon. In any case, get treatment immediately if you see any side effects of a severe allergic response, such as rash, tingling/swelling (particularly of the face/tongue/throat), serious dizziness, inconvenience breathing. This is not a complete rundown of conceivable side effects. In the event that you see different effects not recorded above, contact your specialist or drug specialist. In US – Call your specialist for medicinal counsel about side effects. You might report side effects to FDA.

What are the precautions to take before taking Doryx?

Before taking Doryx, tell your specialist on the off chance that you are adversely affected by it or by different tetracyclines, (for example, minocycline); or on the off chance that you have whatever other allergies. Doryx might contain inactive ingredients, which can cause serious allergic responses or different issues.

Before using Doryx, tell your specialist about your therapeutic history, particularly of: trouble swallowing, problems related to esophagus like hiatal hernia or reflux/heart burn). Before having surgery, tell your specialist or dental specialist that you are taking Doryx. Doryx may make you more sensitive to the sun. Stay away from continuous sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear defensive dress when outside.

Small children older than 8 years may be more sensitive to the side effects of doxycycline, particularly tooth discoloration. Tooth coloration has additionally happened in older kids and adults also. Talk about the dangers and advantages of Doryx with your specialist. This drug is not prescribed for use amid pregnancy. It might hurt an unborn infant. Counsel your specialist for more details. Doryx goes into breast milk yet is unlikely to hurt a nursing newborn child. Counsel your specialist before breast feeding.

What are the commonly occurring interactions?

Drug interactions might change how your prescriptions function or build your danger for severe side effects. This report does not contain all conceivable medication interactions. Keep a list of the considerable number of items you use like nonprescription medications and herbals and show it to your specialist and pharmacist. Try not to begin, stop, or change the dose of any solutions without your specialist’s prescription.

A few items that may interact with tanning booths include: retinoid meds taken by mouth, (for example, acitretin, isotretinoin), barbiturates, (for example, phenobarbital), “blood thinners, (for example, warfarin), digoxin, penicillins, anti-seizure prescriptions, (for example, carbamazepine, phenytoin), strontium, live bacterial vaccines.

Although most antibiotics (counting doxycycline) are unllikely to influence hormonal contraceptives, for example, pills, patch, or ring, a couple of antibiotics, (for example, rifampin, rifabutin) can diminish their viability. This could bring about pregnancy. In the event that you use hormonal contraceptives, approach your specialist or pharmacist for more points of interest. This drug might interfere with certain lab tests (urine catecholamine levels), potentially causing false test outcomes. Ensure your specialists know you use this medication.

What if I overdose?

In the event that overdose is suspected, contact a poison control center immediately.

Important facts

Try not to share this medicine with others. In the event that Doryx is being used to prevent malaria, comprehend that it is still conceivable to get the sickness regardless of the fact that you have used this medication. This medicine has been recommended for your present condition only. Try not to use it later for another infection unless advised to do as such by your specialist. An alternate drug may be important for such cases. Lab and/or medicinal tests, (for example, complete blood county, liver/kidney function test) may be performed occasionally to screen your advancement or check for side effects. Talk to your specialist for more details.

What if I miss a dose?

If you miss a dose, take it when you remember. If it is close to the time to take the following dose, skip the missed dosage and resume your typical dosing schedule. Try not to double the dosage to get up to speed since it can worsen the situation.